CD4 antibody (Biotin)

Catalog No. ABIN951309

This anti-CD4 antibody is a Rat Monoclonal antibody detecting CD4 in FACS. Suitable for Mouse.

Quick Overview for CD4 antibody (Biotin) (ABIN951309)

Target: CD4

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD4 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS)

Clone: CT-CD4

Product Details anti-CD4 Antibody (Biotin)

Specificity: This CT-CD4 monolconal antibody (mAb) recognizes Mouse CD4 (L3T4).

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C. Should this product contain a precipitate we recommend microcentrifugation before use.

Target Details for CD4

Target: CD4

Alternative Name: CD4

Background: CD4 (L3T4) which is expressed on the majority of thymocytes and on the MHC class II restricted subset of mature T cells including Th cells1,2. Mouse CD4 has also been reported to be present on multipotential hematopoietic stem cells, bone marrow myeloid precursors, and intrathymic precursors2,3. As a coreceptor in the TCR complex, CD4 is involved in T cell activation through interaction with MHC class II on APC's and in signal transduction via protein tyrosine kinase lck1.Synonyms: T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4

Gene ID: 12504

NCBI Accession: NP_038516

UniProt: P06332

Pathways: TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events